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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
JPH1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human JPH1.<br>The immunogen is located within amino acids 470 - 520 of JPH1.
- 保存条件:
stored at 4℃ for three months and -20℃, stable for up to one year
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
E, WB, IHC-P
- 抗体英文名:
JPH1 Antibody
- 抗体名:
JPH1 Antibody
- 规格:
0.02mg
JPH1 抗体,JPH1 Antibody,JPH1 抗体,JPH1 Antibody
产品名称:JPH1 抗体-JPH1 Antibody
产品货号:PSI-4917-0.02mg
产品规格:0.02mg
背景资料:JPH1 Antibody: Junctional complexes between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR) are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilins (JPs) are important components of the junctional complexes. JPs are composed of a carboxy-terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the PM. Four JPs have been identified as tissue-specific subtypes derived from different genes: JPH1 is expressed in skeletal muscle, JPH2 is detected throughout all muscle cell types, and JPH3 and JPH4 are predominantly expressed in the brain and contribute to the subsurface cistern formation in neurons. JPH1 is essential for stabilizing the T-tubule and SR membranes to form junctions and provide an environment for the assembly of receptors such as the ryanodine receptor type 1 (RyR1).
保存建议:JPH1 抗体-JPH1 Antibody stored at 4℃ for three months and -20℃, stable for up to one year
应用类型:E, WB, IHC-P
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