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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
IA-1 antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human IA-1.<br>The immunogen is located within amino acids 90 - 140 of IA-1.
- 保存条件:
stored at 4℃ for three months and -20℃, stable for up to one year
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
E, WB
- 抗体英文名:
IA-1 Antibody
- 抗体名:
IA-1 Antibody
- 规格:
0.02mg
IA-1 抗体,IA-1 Antibody,IA-1 抗体,IA-1 Antibody
产品名称:IA-1 抗体-IA-1 Antibody
产品货号:PSI-5415-0.02mg
产品规格:0.02mg
背景资料:IA-1 Antibody: IA-1, also known as INSM1, is an essential five zinc-finger transcription factor that while initially identified from an insulinoma cDNA library, is expressed in the developing nervous system. Specifically, IA-1 is expressed as early as E9.5 in mice in the fore-, mid- and hindbrain, spinal cord, retina, and olfactory bulb. It is thought that IA-1 functions as a transcriptional repressor, and is a part of several signaling pathways including those of Notch and sonic hedgehog in addition to that of Ngn3 during pancreatic endocrine cell differentiation. IA-1 is also expressed in multiple tumors, including the majority of neuroendocrine tumors tested so far as well as nearly 100% of all small cell lung carcinomas, indicating that IA-1 may be an important target in cancer therapy.
保存建议:IA-1 抗体-IA-1 Antibody stored at 4℃ for three months and -20℃, stable for up to one year
应用类型:E, WB
点击:IA-1 抗体-IA-1 Antibody查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验Ia抗原 I region-associated antigen
小白鼠的 H- 2基因复合体的 I区基因的产物。 I-A和 I-E亚区产物,在化学方面已研究得很清楚,即糖蛋白,由α肽链(分子量约为 35,000)和β肽链(分子量为 27,000)以非共价键结合而形成一个分子,在 I- A亚区译码为一条α链( Aα)和二条β链 [Aβ, Ae(也称 Eβ) ],在 I- E亚区译码为一条α链。整个是合成 Aα- Aβ和 Eα- Ae二种 Ia抗原。与 H- 2K, D产物( H- 2抗原)不同,只在一定的细胞如 B细胞、 T细胞部分、巨噬
侵袭性曲霉菌病(Invasive Aspergillosis , IA)现已成为 免疫 力减弱的的儿童病人重要的发病和死亡因素,其预后状况取决于能否早期诊断、采取合适的治疗以及病人本身的抵抗能力。但因为儿童病人的特殊性,成人的一些诊断方法可能并不适合儿童。 例如影像学诊断,对于成人的血液病患者而言,高分辨CT是一种对肺曲霉菌感染的敏感筛查方法,但根据目前积累的数据来看,这些特征性的CT表现可能并不适用于儿童,(1)在一个多中心的回顾性调查中,侵袭性肺曲霉菌感染最常
在免疫反应方面,基于抗原的刺激在体内形成、并与抗原作特异性结合的蛋白质之总称。其化学实质是免疫球蛋白。抗体,按照抗原抗体反应的类型可分别称为沉淀素、凝集素、溶血素、溶菌素、抗毒素、中和抗体等,但这些并不等于有相应的不同抗体存在,一般多只表明抗体反应的多样性而已。抗体在血清中含量最多(体液抗体=humoral antibody);含有某特定抗体的血清称为抗血或免疫血清。
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