- ￥22
- ProSci
- 美国
- PSI-4813-0.02mg
- 2025年07月10日
- E, WB
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CNOT4 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of the human CNOT4.<br>The immunogen is located within amino acids 70 - 120 of CNOT4.
- 保存条件：
stored at 4℃ for three months and -20℃, stable for up to one year
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
E, WB
- 抗体英文名：
CNOT4 Antibody
- 抗体名：
CNOT4 Antibody
- 规格：
0.02mg
CNOT4 抗体，CNOT4 Antibody，CNOT4 抗体,CNOT4 Antibody
产品名称：CNOT4 抗体-CNOT4 Antibody
产品货号：PSI-4813-0.02mg
产品规格：0.02mg
背景资料：CNOT4 Antibody: CNOT4 is a component of the CCR4-NOT transcription complex, a complex that is implicated in the repression of RNA polymerase II transcription. In the CCR4-NOT complex, CNOT4 acts as an E3 ubiquitin-protein ligase and interacts with a subset of E2 ubiquitin-conjugating enzymes through a unique C4C4 RING domain. This E3 ligase activity was shown to be dependent on the selective and specific interaction with the ubiquitin conjugating enzyme UbcH5B. In yeast, mutations in CNOT4 that prevented its interaction with the UbcH5B homolog UBC4 caused increased sensitivity to hydroxyurea, heat shock, and hygromycin B, suggesting that CNOT4 and UbcH5B are involved in stress response in vivo. Multiple isoforms of CNOT4 are known to exist.
保存建议：CNOT4 抗体-CNOT4 Antibody stored at 4℃ for three months and -20℃, stable for up to one year
应用类型：E, WB
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文献和实验
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