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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
BAG-1 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human BAG-1.<br>The immunogen is located within the last 50 amino acids of BAG-1.
- 保存条件:
stored at 4℃ for three months and -20℃, stable for up to one year
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
E, WB, IHC-P, IF
- 抗体英文名:
BAG-1 Antibody
- 抗体名:
BAG-1 Antibody
- 规格:
0.02mg
BAG-1 抗体,BAG-1 Antibody,BAG-1 抗体,BAG-1 Antibody
产品名称:BAG-1 抗体-BAG-1 Antibody
产品货号:PSI-3869-0.02mg
产品规格:0.02mg
背景资料:BAG-1 Antibody: Bcl-2-associated athanogene 1 (BAG-1) was first identified as an anti-apoptotic bcl-2-binding protein. Later it was found to bind the molecular chaperones Hsp70 and Hsc70 through its carboxy-terminal sequence (termed the Bag domain), resulting in the inhibition of the refolding activity of these chaperones. It is thought that by binding and inhibiting these molecular chaperones, BAG-1is able to modulate the expression level of proteins requiring chaperones to fold correctly. One such group of proteins that are affected is glucocorticoid receptors. Other reports have suggested that the level of BAG-1 expression correlates with the aggressiveness of various cancers. Multiple isoforms of BAG-1 are known to exist.
保存建议:BAG-1 抗体-BAG-1 Antibody stored at 4℃ for three months and -20℃, stable for up to one year
应用类型:E, WB, IHC-P, IF
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文献和实验Elastic Bag Model of One-Dimensional Pulsed-Field Gel Electrophoresis (ODPFGE)
Gel electrophoresis is one of the most common techniques used in molecular biology for the separation of DNA molecules. Conventional gel electrophoresis (using a static electric field) does not permit separation of DNA fragments larger
of millions of nonsupport-bound peptides, and can be readily screened using enzyme-linked immunosorbent assay (ELISA) to determine specific sequences that bind to a target antibody. From our studies using peptide libraries, we have found that MAbs exhibit
在免疫反应方面,基于抗原的刺激在体内形成、并与抗原作特异性结合的蛋白质之总称。其化学实质是免疫球蛋白。抗体,按照抗原抗体反应的类型可分别称为沉淀素、凝集素、溶血素、溶菌素、抗毒素、中和抗体等,但这些并不等于有相应的不同抗体存在,一般多只表明抗体反应的多样性而已。抗体在血清中含量最多(体液抗体=humoral antibody);含有某特定抗体的血清称为抗血或免疫血清。
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