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- ProSci
- 美国
- PSI-3863-0.02mg
- 2025年07月12日
- E, WB, IHC-P, IF
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Anti-UNG1 antibody (<strong>3863</strong>) was raised against a peptide corresponding to 13 amino acids near the carboxy terminus of human UNG1. <br> The immunogen is located within the last 50 amino acids of UNG1.
- 保存条件：
stored at 4℃ for three months and -20℃, stable for up to one year
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
E, WB, IHC-P, IF
- 抗体英文名：
UNG1 Antibody
- 抗体名：
UNG1 Antibody
- 规格：
0.02mg
UNG1 抗体，UNG1 Antibody，UNG1 抗体,UNG1 Antibody
产品名称：UNG1 抗体-UNG1 Antibody
产品货号：PSI-3863-0.02mg
产品规格：0.02mg
背景资料：UNG1 Antibody: The human uracil-DNA glycosylase (UNG) gene encodes both mitochondrial (UNG1) and nuclear (UNG2) forms through differentially regulated promotes and alternative splicing. While UNG2 is the major enzyme in the base excision repair pathway that removes uracil residues from nuclear DNA that arise through either misincorporation during replication or cytosine deamination, inhibition of UNG1 by uracil glycosylase inhibitor did not lead to increased levels of spontaneous or induced mitochondrial DNA mutations. However, decreased levels of UNG activity and increased oxidative damage to mitochondrial DNA were seen in older mice, suggesting that mitochondrial DNA repair mechanisms may be involved in various neurodegenerative disorders in an age-dependent manner. This UNG1 antibody will not cross-react with UNG2.
保存建议：UNG1 抗体-UNG1 Antibody stored at 4℃ for three months and -20℃, stable for up to one year
应用类型：E, WB, IHC-P, IF
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