- ￥22
- ProSci
- 美国
- PSI-3117-0.02mg
- 2025年07月16日
- E, WB, IHC-P, IF
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
ATR antibody was raised against a peptide corresponding to 13 amino acids near the center of human ATR.<br>The immunogen is located within amino acids 220 - 270 of ATR.
- 保存条件：
stored at 4℃ for three months and -20℃, stable for up to one year
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
E, WB, IHC-P, IF
- 抗体英文名：
ATR Antibody
- 抗体名：
ATR Antibody
- 规格：
0.02mg
ATR 抗体，ATR Antibody，ATR 抗体,ATR Antibody
产品名称：ATR 抗体-ATR Antibody
产品货号：PSI-3117-0.02mg
产品规格：0.02mg
背景资料：ATR Antibody: The Anthrax toxin receptor (ATR) was initially discovered as the tumor endothelial marker 8 (TEM8). This protein, which exists in three isoforms (36, 40, and 60 kDa), is highly expressed in tumor vessels as well as in the vasculature of developing embryos, suggesting that it may normally play a role in angiogenesis. However, it also acts as the receptor for anthrax toxin. Following the binding of this protein by the protective antigen (PA) of anthrax, PA is cleaved and heptamerizes to form the binding site for both edema factor (EF) and lethal factor (LF). This complex is then endocytosed by the cell; acidification in endosomes allows the release of EF and LF into the cytoplasm where they interfere with MAPK signaling and induce apoptosis.
保存建议：ATR 抗体-ATR Antibody stored at 4℃ for three months and -20℃, stable for up to one year
应用类型：E, WB, IHC-P, IF
点击：ATR 抗体-ATR Antibody查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验Identifying Inhibitors of ATM and ATR Kinase Activities
The Ataxia Telangiectasia mutated (ATM) and the ATM and Rad3-related (ATR) proteins function in partially overlapping DNA damage checkpoint pathways that orchestrate the cellular response to DNA damage. Both proteins belong to a growing
A Human Cell Extract-Based Assay for the Activation of ATM and ATR Checkpoint Kinases
The Ataxia telangiectasia -mutated (ATM) and the ATM-Rad3-related (ATR) kinases are master regulators of the DNA damage-signaling pathways that respond to a wide variety of DNA damage. In this chapter, we describe an in vitro biochemical
在免疫反应方面，基于抗原的刺激在体内形成、并与抗原作特异性结合的蛋白质之总称。其化学实质是免疫球蛋白。抗体，按照抗原抗体反应的类型可分别称为沉淀素、凝集素、溶血素、溶菌素、抗毒素、中和抗体等，但这些并不等于有相应的不同抗体存在，一般多只表明抗体反应的多样性而已。抗体在血清中含量最多（体液抗体=humoral antibody）；含有某特定抗体的血清称为抗血或免疫血清。
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