Lano antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human Lano.<br>The immunogen is located within the last 50 amino acids of Lano.
保存条件:
stored at 4℃ for three months and -20℃, stable for up to one year
背景资料:Lano Antibody: Lano is a member of the LAP (leucine-rich repeats and PDZ) family of proteins that also includes Densin-180, Erbin, and hScribble. The LAP proteins generally contain multiple leucine-rich repeat (LRR) domains which serve to target them to the basolateral membrane of epithelial cells. Lano is unique in that it alone does not possess one or more PDZ (PSD95/DLG/ZO-1) domains as do the other members of the LAP family. However, it can bind to the PDZ domain of Erbin in addition to those of membrane-associated and guanylate kinase (MAGUK) proteins which regulate adhesion and plasticity at cell junctions. It has been suggested that it is through these interaction that these LAP proteins participate in the maintenance of proper embryonic development and integrity of epithelial tissues.
保存建议:Lano 抗体-Lano Antibody stored at 4℃ for three months and -20℃, stable for up to one year