MTBP 抗体-MTBP Antibody

MTBP 抗体，MTBP Antibody，MTBP 抗体,MTBP Antibody

产品名称：MTBP 抗体-MTBP Antibody

产品货号：PSI-2447-0.02mg

产品规格：0.02mg

背景资料：MTBP Antibody: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 network, including Chk2, p53R2, p53AIP1, Noxa, PIDD, PID/MTA2 and MTBP, were recently discovered. The transcriptional activity of p53 is modulated by posttranslational regulations of the p53 protein including stabilization and acetylation. P53 transcriptionally activates MDM2 gene then the translated MDM2 protein binds to p53 and promotes the degradation of p53 leading to lowering the concentration of p53 protein. MDM2 inhibits both p53 mediated G1 arrest and apoptosis. A recently discovered protein termed MTBP was found to bind to MDM2 and to inhibit the modulation effect of MDM2 on p53. MTBP is expressed in a variety of normal tissues.

保存建议：MTBP 抗体-MTBP Antibody stored at 4℃ for three months and -20℃, stable for up to one year

应用类型：E, WB, ICC, IF

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