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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Anti-BACE antibody (<strong>2253</strong>) was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human BACE. <br> The immunogen is located within the last 50 amino acids of BACE.
- 保存条件:
stored at 4℃ for three months and -20℃, stable for up to one year
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
E, WB, ICC, IHC-P, IF
- 抗体英文名:
BACE Antibody
- 抗体名:
BACE Antibody
- 规格:
0.02mg
BACE 抗体,BACE Antibody,BACE 抗体,BACE Antibody
产品名称:BACE 抗体-BACE Antibody
产品货号:PSI-2253-0.02mg
产品规格:0.02mg
背景资料:BACE Antibody: Accumulation of the amyloid-beta (Abeta) plaque in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. Abeta peptide is generated by proteolytic cleavage of the beta-amyloid protein precursor (APP) at beta- and gamma-sites by two proteases. APP is first cleaved by beta-secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99). The C99 fragment serves as substrate for gamma-secretase to generate the 4 kDa amyloid-beta peptide, which is deposited in the brains of all suffers of Alzheimer's disease. The long-sought beta-secretase was recently identified by several groups independently and designated beta-site APP cleaving enzyme (BACE) and aspartyl protease 2 (Asp2). BACE/Asp2 is a novel transmembrane aspartic protease and colocalizes with APP.
保存建议:BACE 抗体-BACE Antibody stored at 4℃ for three months and -20℃, stable for up to one year
应用类型:E, WB, ICC, IHC-P, IF
点击:BACE 抗体-BACE Antibody查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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