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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
ICAD antibody was raised against a peptide corresponding to amino acids near the amino terminus of mouse ICAD.<br>The immunogen is located within the first 50 amino acids of ICAD.
- 保存条件:
stored at 4℃ for three months and -20℃, stable for up to one year
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
E, WB, IHC-P, IF
- 抗体英文名:
ICAD Antibody
- 抗体名:
ICAD Antibody
- 规格:
0.02mg
ICAD 抗体,ICAD Antibody,ICAD 抗体,ICAD Antibody
产品名称:ICAD 抗体-ICAD Antibody
产品货号:PSI-2001-0.02mg
产品规格:0.02mg
背景资料:ICAD Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. A human DNA fragmentation factor (DFF) was identified recently which is cleaved by caspase-3 during apoptosis. Mouse homologue of human DFF was identified as a DNase inhibitor designated ICAD, for inhibitor of caspase-activated DNase. Upon cleavage of DFF/ICAD, a caspase activated deoxyribonuclease (CAD) is released and activated and eventually causes the degradation of DNA in the nuclei. Therefore, the cleavage of CAD inhibitor molecule DFF/ICAD, which causes DNase activation and DNA degradation, is the hallmark of apoptotic cell death.
保存建议:ICAD 抗体-ICAD Antibody stored at 4℃ for three months and -20℃, stable for up to one year
应用类型:E, WB, IHC-P, IF
点击:ICAD 抗体-ICAD Antibody查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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