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AbFlex®BRD9抗体(rAb)AbFlex® BRD9

antibody (rAb)
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  • 询价
  • Active Motif已认证
  • 91427/91428
  • 美国
  • 2026年03月01日
  • WB
  • Rabbit
  • Human
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体名

      AbFlex®BRD9抗体(rAb)

    • 抗体英文名

      AbFlex® BRD9 antibody (rAb)

    • 应用范围

      WB

    • 宿主

      Rabbit

    • 供应商

      Active Motif

    • 库存

      大量

    • 级别

      WB级抗体

    • 保质期

      1年以上

    • 适应物种

      Human

    • 保存条件

      -20度

    • 形态

      液态冻存

    • 亚型

      IgG

    • 免疫原

      This antibody was raised against a peptide within the C-terminal region of human BRD9(bromodomain containing 9).

    • 规格

      100 µg/10 µg

    Background

    AbFlex® antibodies are recombinant antibodies (rAbs) that have been generated using defined DNA sequences to produce highly specific, reproducible antibodies. Each AbFlex antibody contains a 6xHis Tag, a Biotinylation Tag for enzymatic biotin conjugation using the biotin ligase, BirA, and a sortase recognition motif (LPXTG) to attach a variety of labels directly to the antibody including fluorophores, enzymatic substrates (HRP, AP), peptides, drugs as well as solid supports.

    AbFlex® BRD9 antibody was expressed as full-length IgG with mouse immunoglobulin heavy and light chains (IgG2a isotype) in mammalian 293 cells.

    BRD9 (bromodomain containing 9) belongs to the BET subclass of proteins, which are characterized by two N-terminal bromodomains and one ET (Extra Terminal) domain. BRDs associate with chromatin through their bromodomains that recognize acetylated histone lysine residues. Bromodomains function as ‘readers’ of these epigenetic histone marks and regulate chromatin structure and gene expression by linking associated proteins to the acetylated nucleosomal targets. The ET domain functions as a protein binding motif and exerts atypical serine-kinase activity. The BET family consists of at least four members in mouse and human, BRD2 (also referred to as FSRG1, RING3), BRD3 (FSRG2, ORFX), BRD4 (FSRG4, MCAP/HUNK1), and BRDT (FSRG3, BRD6) that function in the regulation of transcriptional activation and chromatin remodeling. There are five isoforms of BRD9 that are produced by alternative splicing.

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    图标文献和实验
    相关实验
    • secondary antibody review -- data from 99 publications

      cytometry   used as a control to detect cell responses targeted antigen   7       Alexa Fluor 488         7       Cy3         8 goat IgG   Alexa Fluor 488   1:2000 detect antibody binding in human embryonic kidney 293T cells Invitrogen 9 donkey

    • Using Phospho‐Motif Antibodies to Determine Kinase Substrates

      comprising both the phosphorylated residue and the surrounding residues that determine kinase specificity, with degenerate residues taking up the remaining positions. Currently, several categories of phospho?motif antibody are commercially available

    • Exploring Zebrafish Genomic, Functional and Phenotypic Data Using ZFIN

      , gene expression, mutants, morphants, transgenics, anatomical structures, and antibodies. ZFIN's GBrowse genome viewer, BLAST, and protocol and antibody wikis are also discussed. Curr. Protoc. Bioinform. 31:1.18.1?1.18.44. © 2010 by John Wiley & Sons

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