- $15000
- Leading Biology
- 美国
- PK54241M2
- 2025年07月16日
10 年钻石会员
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 保存条件：
Stable for 1 year at -4261°C or below from date of shipment.
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 规格：
1 mg
蛋白长度：A DNA sequence encoding the cynomolgus/rhesus MET (A0A2K5UM36-1 / NP_001162100.2) (Met1-Thr932) was expressed with a polyhistidine tag at the C-terminus. Cynomolgus and Rhesus MET sequences are identical.
性质：
表达系统：HEK293 Cells
种属：Cynomolgus, Rhesus
氨基酸序：Met1-Thr932
标签类型：C-His
分子量：The recombinant cynomolgus / rhesus MET comprises 919 amino acids and has a calculated molecular mass of 103.1 KDa. The apparent molecular mass of it is approximately 128.2, 77.6 and 45.7 KDa in SDS-PAGE under reducing conditions.
活性：Measured by its binding ability in a functional ELISA. Immobilized Cynomolgus HGF (Cat:PK54072M0) at 2 μg/ml (100 μl/well) can bind Cynomolgus c-MET His (Cat:PK54241M2), the ECof Cynomolgus c-MET His is 15-60 ng/mL.
内毒素：< 1.0 EU per μg of the protein as determined by the LAL method.
基因名称：MET proto-oncogene, receptor tyrosine kinase
通用名：MET
蛋白序参考：NP_001162100.1
总结：Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR protein is produced as a single-chain precursor, and HGF is the only known ligand. Normal HGF/HGFR signaling is essential for embryonic development, tissue repair, or wound healing, whereas aberrantly active HGFR has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes. HGFR protein is a multifaceted regulator of growth, motility, and invasion, and is normally expressed by cells of epithelial origin. Preclinical studies suggest that targeting aberrant HGFR signaling could be an attractive therapy in cancer.
形式：Lyophilized
纯度：> 95 % as determined by SDS-PAGE.
储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
储存溶液：Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
别名：
性质：
表达系统：HEK293 Cells
种属：Cynomolgus, Rhesus
氨基酸序：Met1-Thr932
标签类型：C-His
分子量：The recombinant cynomolgus / rhesus MET comprises 919 amino acids and has a calculated molecular mass of 103.1 KDa. The apparent molecular mass of it is approximately 128.2, 77.6 and 45.7 KDa in SDS-PAGE under reducing conditions.
活性：Measured by its binding ability in a functional ELISA. Immobilized Cynomolgus HGF (Cat:PK54072M0) at 2 μg/ml (100 μl/well) can bind Cynomolgus c-MET His (Cat:PK54241M2), the ECof Cynomolgus c-MET His is 15-60 ng/mL.
内毒素：< 1.0 EU per μg of the protein as determined by the LAL method.
基因名称：MET proto-oncogene, receptor tyrosine kinase
通用名：MET
蛋白序参考：NP_001162100.1
总结：Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR protein is produced as a single-chain precursor, and HGF is the only known ligand. Normal HGF/HGFR signaling is essential for embryonic development, tissue repair, or wound healing, whereas aberrantly active HGFR has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes. HGFR protein is a multifaceted regulator of growth, motility, and invasion, and is normally expressed by cells of epithelial origin. Preclinical studies suggest that targeting aberrant HGFR signaling could be an attractive therapy in cancer.
形式：Lyophilized
纯度：> 95 % as determined by SDS-PAGE.
储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
储存溶液：Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
别名：
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
c-MET Protein, Cynomolgus, Rhesus, Recombinant (His Tag)
$15000
