- $15000
- Leading Biology
- 美国
- PK54159M2
- 2025年07月13日
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- 详细信息
- 技术资料
- 保存条件：
Stable for 1 year at -4179°C or below from date of shipment.
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 规格：
1 mg
蛋白长度：A DNA sequence encoding the rhesus PVR (NP_001036851.1) extracellular domain (Met 1-Asn 343) was expressed with a C-terminal polyhistidine tag.
性质：
表达系统：HEK293 Cells
种属：Rhesus
氨基酸序：Met1-Asn343
标签类型：C-His
分子量：The recombinant rhesus PVR consists of 327 amino acids and has a calculated molecular mass of 35.8 kDa.
活性：1. Measured by its binding ability in a functional ELISA. Immobilized Rhesus CD155 at 2 μg/ml (100 μl/well) can bind human CD226 with a linear range of 1.28-32 ng/ml. 2. Immobilized TIGIT Protein, Human, Recombinant (mFc Tag)(Cat:PH51579M4) at 2 μg/ml (100 μl/well) can bind CD155/PVR Protein, Rhesus, Recombinant (His Tag)(Cat:PK54159M2), the ECof CD155/PVR Protein, Rhesus, Recombinant (His Tag)is 200-900 ng/mL.
内毒素：< 1.0 EU per μg of the protein as determined by the LAL method.
基因名称：poliovirus receptor
通用名：PVR
蛋白序参考：NP_001036851.1
总结：CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhesion, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.
形式：Lyophilized
纯度：> 98 % as determined by SDS-PAGE.
储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
储存溶液：Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
别名：
性质：
表达系统：HEK293 Cells
种属：Rhesus
氨基酸序：Met1-Asn343
标签类型：C-His
分子量：The recombinant rhesus PVR consists of 327 amino acids and has a calculated molecular mass of 35.8 kDa.
活性：1. Measured by its binding ability in a functional ELISA. Immobilized Rhesus CD155 at 2 μg/ml (100 μl/well) can bind human CD226 with a linear range of 1.28-32 ng/ml. 2. Immobilized TIGIT Protein, Human, Recombinant (mFc Tag)(Cat:PH51579M4) at 2 μg/ml (100 μl/well) can bind CD155/PVR Protein, Rhesus, Recombinant (His Tag)(Cat:PK54159M2), the ECof CD155/PVR Protein, Rhesus, Recombinant (His Tag)is 200-900 ng/mL.
内毒素：< 1.0 EU per μg of the protein as determined by the LAL method.
基因名称：poliovirus receptor
通用名：PVR
蛋白序参考：NP_001036851.1
总结：CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhesion, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.
形式：Lyophilized
纯度：> 98 % as determined by SDS-PAGE.
储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
储存溶液：Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
别名：
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CD155/PVR Protein, Rhesus, Recombinant (His Tag)
$15000
