- $15000
- Leading Biology
- 美国
- PK53923M2
- 2025年07月14日
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- 详细信息
- 技术资料
- 保存条件：
Stable for 1 year at -3943°C or below from date of shipment.
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 规格：
1 mg
蛋白长度：A DNA sequence encoding the rhesus IL6R (XP_001114404.1) (Met1-Pro365) was expressed with a polyhistidine tag at the C-terminus.
性质：
表达系统：HEK293 Cells
种属：Rhesus
氨基酸序：Met1-Pro365
标签类型：C-His
分子量：The recombinant rhesus IL6R consists of 357 amino acids and predicts a molecular mass of 39.6 kDa.
活性：1.Measured by its binding ability in a functional ELISA. 2.Immobilized rhesus IL6R (Cat:PK53923M2) at 10μg/mL (100μL/well) can bind human IL6 (Cat:10395-HNAE), the ECof human IL6 is 5-50 ng/mL.
内毒素：< 1.0 EU per μg protein as determined by the LAL method.
基因名称：interleukin 6 receptor
通用名：IL6R
蛋白序参考：XP_001114404.1
总结：Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-6 receptor (SIL-6R) acts as an agonist of IL-6 activity. In the IL-6R/CD126/IL6R system, both a membrane-bound IL-6R and a SIL-6R protein can mediate IL-6 signals into the cells through the interaction of gp130. The resulting IL-6/sIL-6R protein complex is also capable of binding to gp130 and inducing intracellular signaling. Through this so-called 'trans-signaling' mechanism, IL-6 can stimulate cells that lack an endogenous mIL-6R. High levels of IL-6 and SIL-6R have been reported in several chronic inflammatory and autoimmune diseases as well as in cancer.
形式：Lyophilized
纯度：> 95 % as determined by SDS-PAGE.
储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
储存溶液：Lyophilized from sterile Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
别名：
性质：
表达系统：HEK293 Cells
种属：Rhesus
氨基酸序：Met1-Pro365
标签类型：C-His
分子量：The recombinant rhesus IL6R consists of 357 amino acids and predicts a molecular mass of 39.6 kDa.
活性：1.Measured by its binding ability in a functional ELISA. 2.Immobilized rhesus IL6R (Cat:PK53923M2) at 10μg/mL (100μL/well) can bind human IL6 (Cat:10395-HNAE), the ECof human IL6 is 5-50 ng/mL.
内毒素：< 1.0 EU per μg protein as determined by the LAL method.
基因名称：interleukin 6 receptor
通用名：IL6R
蛋白序参考：XP_001114404.1
总结：Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-6 receptor (SIL-6R) acts as an agonist of IL-6 activity. In the IL-6R/CD126/IL6R system, both a membrane-bound IL-6R and a SIL-6R protein can mediate IL-6 signals into the cells through the interaction of gp130. The resulting IL-6/sIL-6R protein complex is also capable of binding to gp130 and inducing intracellular signaling. Through this so-called 'trans-signaling' mechanism, IL-6 can stimulate cells that lack an endogenous mIL-6R. High levels of IL-6 and SIL-6R have been reported in several chronic inflammatory and autoimmune diseases as well as in cancer.
形式：Lyophilized
纯度：> 95 % as determined by SDS-PAGE.
储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
储存溶液：Lyophilized from sterile Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
别名：
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IL-6R Protein, Rhesus, Recombinant (His Tag)
$15000
