Periostin Protein, Mouse, Recombinant (His Tag)

Periostin Protein, Mouse, Reco

mbinant (His Tag)
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  • $3865
  • Leading Biology
  • 美国
  • PM53517M2
  • 2025年07月15日
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    • 详细信息
    • 技术资料
    • 保存条件

      Stable for 1 year at -3537°C or below from date of shipment.

    • 保质期

      1-2年

    • 供应商

      安诺伦(北京)生物科技有限公司

    • 规格

      100 ug

    蛋白长度:A DNA sequence encoding the full length of mouse POSTN (NP_056599.1) (Met 1-Gln 811) was expressed, with a polyhistidine tag at the C-terminus.

    性质:

    表达系统:HEK293 Cells

    种属:Mouse

    氨基酸序:Met1-Gln811

    标签类型:C-His

    分子量:The secreted recombinant mouse POSTN consists of 799 amino acids and has a calculated molecular mass of 89 kDa. The apparent molecular mass of rmPOSTN is approximately 80-85 kDa in SDS-PAGE under reducing conditions.

    活性:Measured by its ability to induce adhesion of ATDC5 mouse chondrogenic cells.When cells are added to POSTN-His coated plates (10 μg/mL, 100 μL/well), approximately >40% will adhere specifically after 30 minutes at 37℃.

    内毒素:< 1.0 EU per μg of the protein as determined by the LAL method.

    基因名称:periostin, osteoblast specific factor

    通用名:POSTN

    蛋白序参考:NP_056599.1

    总结:Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, as well as collagen fibrillogenesis. Postn is expressed in unique growth centers during embryonic development where it facilitates epithelial-mesenchymal transition (EMT) of select cell populations undergoing reorganization. In the adult, Postn expression is specifically induced in areas of tissue injury or areas with ongoing cellular re-organization. In the adult heart Postn is induced in the ventricles following myocardial infarction, pressure overload stimulation, or generalized cardiomyopathy. Although the detailed function of Postn is still unclear, Postn-integrin interaction is thought to be involved in tumor development. Postn is frequently overexpressed in various types of human cancers, stimulating metastatic growth by promoting cancer cell survival, invasion and angiogenesis, and can be a useful marker to predict the behavior of cancer.

    形式:Lyophilized

    纯度:> 92 % as determined by SDS-PAGE.

    储存条件:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

    储存溶液:Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.

    别名:A630052E07Rik Protein, Mouse; AI747096 Protein, Mouse; OSF-2 Protein, Mouse; Osf2 Protein, Mouse; peri Protein, Mouse; PLF Protein, Mouse; PN Protein, Mouse

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