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- 详细信息
- 技术资料
- 保存条件：
Stable for 1 year at -3134°C or below from date of shipment.
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 规格：
100 ug
蛋白长度：A DNA sequence encoding the extracellular domain of mouse PDCD1LG2 (Q9WUL5) (Met1-Arg219) was expressed, with a C-terminal polyhistidine tag. The purified protein was biotinylated in vitro.
性质：
表达系统：HEK293 Cells
种属：Mouse
氨基酸序：Met1-Arg219
标签类型：C-His
分子量：The recombinant human PDCD1LG2 consists of 211 amino acids and predicts a molecular mass of 24 kDa.
活性：1. Measured by its binding ability in a functional ELISA. 2. Immobilized mouse PD-L2-his at 10 μg/mL (100 μl/well) can bind mouse PD1-Fc. The ECof mouse PD1-Fc is 1.63 μg/mL.
内毒素：< 1.0 EU per μg protein as determined by the LAL method.
基因名称：programmed cell death 1 ligand 2
通用名：PDCD1LG2
蛋白序参考：
总结：Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally consists of an extracellular region containing one V-like and one C-like Ig domain, a transmembrane region, and a short cytoplasmic domain. PD-L2 is expressed on antigen presenting cells, placental endothelium and medullary thymic epithelial cells, and can be induced by LPS in B cells, INF-γ in monocytes, or LPS plus IFN-γ in dendritic cells. The CD28 and B7 protein families are critical regulators of immune responses. PD-L2 and PD-L1 are two ligands for PD-1, member of the CD28/CTLA4 family expressed on activated lymphoid cells, and thus provide signals for regulating T cell activation and immune tolerance. The interaction of B7-DC/PD-1 exhibited a 2-6-fold higher affinity compared with the interaction of B7-H1/PD-1.
形式：Lyophilized
纯度：> 90 % as determined by SDS-PAGE.
储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
储存溶液：Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
别名：B7-DC Protein, Mouse; Btdc Protein, Mouse; F730015O22Rik Protein, Mouse; PD-L2 Protein, Mouse
性质：
表达系统：HEK293 Cells
种属：Mouse
氨基酸序：Met1-Arg219
标签类型：C-His
分子量：The recombinant human PDCD1LG2 consists of 211 amino acids and predicts a molecular mass of 24 kDa.
活性：1. Measured by its binding ability in a functional ELISA. 2. Immobilized mouse PD-L2-his at 10 μg/mL (100 μl/well) can bind mouse PD1-Fc. The ECof mouse PD1-Fc is 1.63 μg/mL.
内毒素：< 1.0 EU per μg protein as determined by the LAL method.
基因名称：programmed cell death 1 ligand 2
通用名：PDCD1LG2
蛋白序参考：
总结：Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally consists of an extracellular region containing one V-like and one C-like Ig domain, a transmembrane region, and a short cytoplasmic domain. PD-L2 is expressed on antigen presenting cells, placental endothelium and medullary thymic epithelial cells, and can be induced by LPS in B cells, INF-γ in monocytes, or LPS plus IFN-γ in dendritic cells. The CD28 and B7 protein families are critical regulators of immune responses. PD-L2 and PD-L1 are two ligands for PD-1, member of the CD28/CTLA4 family expressed on activated lymphoid cells, and thus provide signals for regulating T cell activation and immune tolerance. The interaction of B7-DC/PD-1 exhibited a 2-6-fold higher affinity compared with the interaction of B7-H1/PD-1.
形式：Lyophilized
纯度：> 90 % as determined by SDS-PAGE.
储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
储存溶液：Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
别名：B7-DC Protein, Mouse; Btdc Protein, Mouse; F730015O22Rik Protein, Mouse; PD-L2 Protein, Mouse
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PD-L2 Protein, Mouse, Recombinant (His Tag), Biotinylated
$4675
