- $3475
- Leading Biology
- 美国
- PM52787M3
- 2025年07月03日
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- 详细信息
- 技术资料
- 保存条件：
Stable for 1 year at -2807°C or below from date of shipment.
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 规格：
100 ug
蛋白长度：A DNA sequence encoding the mature form of mouse FIGF (P97946) (Phe 98-Ser 206) was fused with the Fc region of human IgG1 at the N-terminus.
性质：
表达系统：HEK293 Cells
种属：Mouse
氨基酸序：Phe98-Ser206
标签类型：N-hFc
分子量：The recombinant mouse FIGF/Fc is a disulfide-linked homodimer. The reduced monomer comprises 369 amino acids and has a calculated molecular mass of 40.6 kDa.The apparent molecular mass of the protein is approximately 45 and 36 kDa in SDS-PAGE under reducing conditions.
活性：1. Measured by its binding ability in a functional ELISA. 2. Immobilized human VEGFR3-His (Cat:PH51844M2) at 10 μg/mL (100 μl/well) can bind mouse Fc-VEGFD, The ECof mouse Fc-VEGFD is 49 ng/mL. 3. Immobilized mouse VEGFR3-His (Cat:PM52865M2) at 10 μg/mL (100 μl/well) can bind mouse Fc-VEGFD, The ECof mouse Fc-VEGFD is 44 ng/mL.
内毒素：< 1.0 EU per μg of the protein as determined by the LAL method.
基因名称：c-fos induced growth factor (vascular endothelial growth factor D)
通用名：VEGFD
蛋白序参考：
总结：Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. FIGF protein is secreted as a non-covelent homodimer in an antiparallel fashion. Human FIGF protein is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs and skin. FIGF protein is structurally and functionally similar to VEGF-C. Therefore, FIGF protein binds and activates VEGFR-2 (Flk1) and VEGFR-3 (Flt4) receptors, and may particularly be involved in cancers, such as breast cancer, epithelial ovarian carcinoma and so on.
形式：Lyophilized
纯度：> 95 % as determined by SDS-PAGE.
储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
储存溶液：Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
别名：AI325264 Protein, Mouse; VEGF-D Protein, Mouse; Vegfd Protein, Mouse
性质：
表达系统：HEK293 Cells
种属：Mouse
氨基酸序：Phe98-Ser206
标签类型：N-hFc
分子量：The recombinant mouse FIGF/Fc is a disulfide-linked homodimer. The reduced monomer comprises 369 amino acids and has a calculated molecular mass of 40.6 kDa.The apparent molecular mass of the protein is approximately 45 and 36 kDa in SDS-PAGE under reducing conditions.
活性：1. Measured by its binding ability in a functional ELISA. 2. Immobilized human VEGFR3-His (Cat:PH51844M2) at 10 μg/mL (100 μl/well) can bind mouse Fc-VEGFD, The ECof mouse Fc-VEGFD is 49 ng/mL. 3. Immobilized mouse VEGFR3-His (Cat:PM52865M2) at 10 μg/mL (100 μl/well) can bind mouse Fc-VEGFD, The ECof mouse Fc-VEGFD is 44 ng/mL.
内毒素：< 1.0 EU per μg of the protein as determined by the LAL method.
基因名称：c-fos induced growth factor (vascular endothelial growth factor D)
通用名：VEGFD
蛋白序参考：
总结：Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. FIGF protein is secreted as a non-covelent homodimer in an antiparallel fashion. Human FIGF protein is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs and skin. FIGF protein is structurally and functionally similar to VEGF-C. Therefore, FIGF protein binds and activates VEGFR-2 (Flk1) and VEGFR-3 (Flt4) receptors, and may particularly be involved in cancers, such as breast cancer, epithelial ovarian carcinoma and so on.
形式：Lyophilized
纯度：> 95 % as determined by SDS-PAGE.
储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
储存溶液：Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
别名：AI325264 Protein, Mouse; VEGF-D Protein, Mouse; Vegfd Protein, Mouse
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VEGFD Protein, Mouse, Recombinant (hFc Tag)
$3475
