carboxylesterase 2/CES2 Protein, Human, Recombinant (His Tag)

carboxylesterase 2/CES2 Protei

n, Human, Recombinant (His Tag)
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  • $3215
  • Leading Biology
  • 美国
  • PH52419M2
  • 2025年07月10日
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    • 详细信息
    • 技术资料
    • 保存条件

      Stable for 1 year at -2439°C or below from date of shipment.

    • 保质期

      1-2年

    • 供应商

      安诺伦(北京)生物科技有限公司

    • 规格

      50 ug

    蛋白长度:A DNA sequence encoding the human CES2 isoform 1 (O00748-1) (Met 1-Leu 559) was expressed, with a C-terminal polyhistidine tag.

    性质:

    表达系统:HEK293 Cells

    种属:Human

    氨基酸序:Met1-Leu559

    标签类型:C-His

    分子量:The secreted recombinant human CES2 comprises 544 amino acids with a predicted molecular mass of 60.4 kDa, as estimated in SDS-PAGE under reducing conditions.

    活性:Measured by its ability to hydrolyze p-nitrophenylacetate.The specific activity is >20000 pmols/min/ug.

    内毒素:< 1.0 EU per μg of the protein as determined by the LAL method.

    基因名称:carboxylesterase 2

    通用名:CES2

    蛋白序参考:

    总结:Carboxylesterase 2 (CES2) is a member of the carboxylesterase family and belongs to the multigene family. Carboxylesterase 2 is responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and beroin. It also serves to hydrolyze long-chain fatty acid esters and thioesters. It is speculated that carboxylesterases may play a role in lipid metabolism and the blood-brain barrier system and together with isform 1, are a serine esterase involved in both drug metabolism and activation. Human carboxylesterase 2 is commonly expressed in tumor tissues and irinotecan, a topoisomerase I inhibitor commonly used in the treatment of many solid tumors.

    形式:Lyophilized

    纯度:> 95 % as determined by SDS-PAGE.

    储存条件:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

    储存溶液:Lyophilized from sterile 50mM NaAc, 150mM NaCl, 10% Glycerol, pH 5.5 Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.

    别名:CE-2 Protein, Human; CES2A1 Protein, Human; iCE Protein, Human; PCE-2 Protein, Human

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