- $15000
- Leading Biology
- 美国
- PH52025E0
- 2025年07月15日
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- 详细信息
- 技术资料
- 保存条件：
Stable for 1 year at -2045°C or below from date of shipment.
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 规格：
1 mg
蛋白长度：A DNA sequence encoding human CXCL14 (O95715) (Ser35-Glu111) was expressed with a N-terminal Met.
性质：
表达系统：E. coli
种属：Human
氨基酸序：Ser35-Glu111
标签类型：No tag
分子量：The recombinant human CXCL14 consists of 77 amino acids and predicts a molecular mass of 9.4 KDa. It migrates as an approximately 15 KDa band in SDS-PAGE under reducing conditions.
活性：At Leading Biology, the biological activity of a recombinant protein is routinely measured using a bioassay, e.g. chemotaxis or cell proliferation assay, enzyme assay, or a functional ELISA. When a recombinant protein is an enzyme, specific activity is derived from an enzymatic assay. Each enzyme is tested for potency by cleavage of a substrate. We are in the process of updating the biological activity data. If you have any questions regarding this update, please feel free to contact our technical support team.
内毒素：Please contact us for more information.
基因名称：chemokine (C-X-C motif) ligand 14
通用名：CXCL14
蛋白序参考：
总结：CXCL14 is a CXC chemokine family that exhibits antimicrobial activity and contains an amphipathic cationic alpha-helical region in the C-terminus, a characteristic structure of antimicrobial peptides (AMPs). CXCL14 is involved in cell recruitment, migration, activation, and homing in liver diseases and have been shown to be upregulated during acute liver injury in animal models. The CXC chemokine ligand 14 (CXCL14) had been show highly expressed in tumor-associated stromal cells, promoting tumor cell growth, and invasion. The stimulation of dysregulated CXCL14 expression by P. gingivalis may help promote dysbiosis and the development of chronic periodontitis. The level of CXCL14 expression may be a valuable adjuvant parameter to predict the prognosis of patients with oral carcinoma and may be a potential therapeutic target.
形式：Lyophilized
纯度：> 90 % as determined by SDS-PAGE.
储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
储存溶液：Lyophilized from sterile 100mM NaH2PO4, 1M NaCl, pH 6.5. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
别名：BMAC Protein, Human; BRAK Protein, Human; KEC Protein, Human; KS1 Protein, Human; MIP-2g Protein, Human; MIP2G Protein, Human; NJAC Protein, Human; SCYB14 Protein, Human
性质：
表达系统：E. coli
种属：Human
氨基酸序：Ser35-Glu111
标签类型：No tag
分子量：The recombinant human CXCL14 consists of 77 amino acids and predicts a molecular mass of 9.4 KDa. It migrates as an approximately 15 KDa band in SDS-PAGE under reducing conditions.
活性：At Leading Biology, the biological activity of a recombinant protein is routinely measured using a bioassay, e.g. chemotaxis or cell proliferation assay, enzyme assay, or a functional ELISA. When a recombinant protein is an enzyme, specific activity is derived from an enzymatic assay. Each enzyme is tested for potency by cleavage of a substrate. We are in the process of updating the biological activity data. If you have any questions regarding this update, please feel free to contact our technical support team.
内毒素：Please contact us for more information.
基因名称：chemokine (C-X-C motif) ligand 14
通用名：CXCL14
蛋白序参考：
总结：CXCL14 is a CXC chemokine family that exhibits antimicrobial activity and contains an amphipathic cationic alpha-helical region in the C-terminus, a characteristic structure of antimicrobial peptides (AMPs). CXCL14 is involved in cell recruitment, migration, activation, and homing in liver diseases and have been shown to be upregulated during acute liver injury in animal models. The CXC chemokine ligand 14 (CXCL14) had been show highly expressed in tumor-associated stromal cells, promoting tumor cell growth, and invasion. The stimulation of dysregulated CXCL14 expression by P. gingivalis may help promote dysbiosis and the development of chronic periodontitis. The level of CXCL14 expression may be a valuable adjuvant parameter to predict the prognosis of patients with oral carcinoma and may be a potential therapeutic target.
形式：Lyophilized
纯度：> 90 % as determined by SDS-PAGE.
储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
储存溶液：Lyophilized from sterile 100mM NaH2PO4, 1M NaCl, pH 6.5. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
别名：BMAC Protein, Human; BRAK Protein, Human; KEC Protein, Human; KS1 Protein, Human; MIP-2g Protein, Human; MIP2G Protein, Human; NJAC Protein, Human; SCYB14 Protein, Human
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CXCL14 Protein, Human, Recombinant
$15000
