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- PH51659Y2
- 2025年07月15日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Stable for 1 year at -1679°C or below from date of shipment.
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 规格：
100 ug
性质：
表达系统：Yeast
种属：Human
氨基酸序：Cys24-Glu189
标签类型：C-His
分子量：The recombinant human IFNA1 consists of 176 amino acids and predicts a molecular mass of 20.8 kDa.
活性：Measured in antiviral assays using WISH cells infected with vesicular stomatitis virus.The EDfor this effect is 40-200pg/mL.
内毒素：Please contact us for more information.
基因名称：interferon, alpha 1
通用名：IFNA1
蛋白序参考：NP_076918.1
总结：IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites, or tumor cells. They belong to the large class of glycoproteins known as cytokines. IFNs stimulate the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs can activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes, and they also increase the ability of uninfected host cells to resist new infection by the virus. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon is produced by mitogen- or antigen-stimulated T lymphocytes. IFNA1 is produced by macrophages and has antiviral activities.
形式：Lyophilized
纯度：> 95 % as determined by SDS-PAGE.
储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
储存溶液：Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
别名：IFL Protein, Human; IFN Protein, Human; IFN-ALPHA Protein, Human; IFN-alphaD Protein, Human; IFNA13 Protein, Human; IFNA Protein, Human
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文献和实验Protein Engineering of Interferon Alphas
differences in these proteins may be responsible for a significant variety of biological actions. Understanding the structure and function of human IFN-α is very important. Recombinant techniques are important tools for the production and modification of IFN
motifs located prevalently in the 3′ untranslated regions of target messenger RNAs (mRNA). Interferon-alpha-2a (IFNα) induces a large set of protein coding genes mediating antiproliferative and antiviral responses. Here we use a global microarray-based
A Novel Plant Cell Bioproduction Platform for High-Yield Secretion of Recombinant Proteins
extends the serum half-life of small therapeutic proteins, such as interferon α2b or human growth hormone, without significantly impairing their bioactivities and the tag greatly enhances solubility.
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