BMP-2 Protein, Human, Mouse, R

蛋白长度：A DNA sequence encoding the mature form of human / mouse / rat / rhesus / canine BMP2 (NP_001191.1) (Gln 283-Arg 396) was fused with the Fc region of human IgG1 at the N-terminus. The mature form sequences of human, mouse, rat, rhesus and canine BMP2 are identical.

性质：

表达系统：HEK293 Cells

种属：Human, Mouse, Rat, Rhesus, Canine

氨基酸序：Gln283-Arg396

标签类型：N-hFc

分子量：The recombinant human / mouse / rat / rhesus / canine BMP2 consists of 351 amino acids and has a predicted molecular mass of 39.5 kDa.

活性：Measured by its ability to bind recombinant human BMPR-II-Fc (Cat:PH52301M4) in a functional ELISA.

内毒素：< 1.0 EU per μg of the protein as determined by the LAL method.

基因名称：bone morphogenetic protein 2

通用名：BMP2

蛋白序参考：NP_001191.1

总结：BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.

形式：Lyophilized

纯度：> 95 % as determined by SDS-PAGE.

储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

储存溶液：Lyophilized from sterile 100mM Glycine, 10mM NaCl, 50mM Tris, pH 7.5 Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.

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