CD48 Protein, Human, Recombina

蛋白长度：A DNA sequence encoding the human CD48 (NP_001769.2) (Met 1-Ser 220) with a C-terminal polyhistidine tag was expressed.

性质：

表达系统：HEK293 Cells

种属：Human

氨基酸序：Met1-Ser220

标签类型：C-His

分子量：The secreted recombinant human CD48 comprises 205 amino acids with a predicted molecular mass of 23.8 kDa. As a result of glycosylation, rhCD48 migrates as an approximately 40 kDa band in SDS-PAGE under reducing conditions.

活性：Measured by its binding ability in a functional ELISA. Immobilized human CD48 at 10 μg/ml (100 μl/well) can bind recombinant human 2B4 / CD244 with a linear range of 0.004-0.4 μg/ml.

内毒素：< 1.0 EU per μg of the protein as determined by the LAL method.

基因名称：CD48 molecule

通用名：CD48

蛋白序参考：NP_001769.2

总结：Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.

形式：Lyophilized

纯度：> 95 % as determined by SDS-PAGE.

储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

储存溶液：Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.

别名：BCM1 Protein, Human; BLAST Protein, Human; Blast-1 Protein, Human; BLAST1 Protein, Human; hCD48 Protein, Human; mCD48 Protein, Human; MEM-102 Protein, Human; SLAMF2 Protein, Human