EphA1 Protein, Human, Recombin

蛋白长度：A DNA sequence encoding the human EPHA1 (EAL23789.1) (Met1-Glu547) was expressed with the Fc region of human IgG1 at the C-terminus.

性质：

表达系统：HEK293 Cells

种属：Human

氨基酸序：Met1-Glu547

标签类型：C-hFc

分子量：The recombinant human EPHA1 consists 760 amino acids and predicts a molecular mass of 83.3 kDa.

活性：Measured by its binding ability in a functional ELISA.Immobilized human EFNA1-His(Cat:PH51296M2) at 10 μg/ml (100 μl /well) can bind human EPHA1-Fc, The ECof human EPHA1-Fc is 10-30 ng/ml.

内毒素：< 1.0 EU per μg protein as determined by the LAL method.

基因名称：EPH receptor A1

通用名：EPHA1

蛋白序参考：EAL23789.1

总结：EPHA1 or EPH receptor A1 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. An important role of Eph receptors and their ligands ephrins is to mediate cell-contact-dependent repulsion. Eph receptors and ephrins also act at boundaries to channel neuronal growth cones along specific pathways, restrict the migration of neural crest cells, and via bidirectional signaling prevent intermingling between hindbrain segments. Eph receptors and ephrins can also trigger an adhesive response of endothelial cells and are required for the remodeling of blood vessels. Eph receptors and ephrins have emerged as key regulators of the repulsion and adhesion of cells that underlie the establishment, maintainence, and remodeling of patterns of cellular organization. The ephrins and Eph receptors are implicated as positional labels that may guide the development of neural topographic maps.

形式：Lyophilized

纯度：> 90 % as determined by SDS-PAGE.

储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

储存溶液：Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.

别名：EPH Protein, Human; EPHA9 Protein, Human; EPHT Protein, Human; EPHT1 Protein, Human