- $3865
- Leading Biology
- 美国
- PH50273M4
- 2025年07月15日
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- 详细信息
- 技术资料
- 保存条件：
Stable for 1 year at -293°C or below from date of shipment.
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 规格：
100 ug
蛋白长度：A DNA sequence encoding the human RNF43 (NP_060233.3) (Met1-Tyr197) was expressed with the Fc region of human IgG1 at the C-terminus.
性质：
表达系统：HEK293 Cells
种属：Human
氨基酸序：Met1-Tyr197
标签类型：C-hFc
分子量：The recombinant human RNF43/Fc comprises 412 amino acids and has a predicted molecular mass of 45.8 kDa. The apparent molecular mass of the protein is approximately 52 kDa in SDS-PAGE under reducing conditions.
活性：Measured by its binding ability in a functional ELISA. Immobilized Human RSPO3 His (Cat:PH50710M2) at 2 μg/ml (100 μl/well) can bind Human RNF43 hFc (Cat:PH50273M4), the ECof Human RNF43 hFc is 3.0-12.0 ng/mL
内毒素：< 1.0 EU per μg of the protein as determined by the LAL method.
基因名称：ring finger protein 43
通用名：RNF43
蛋白序参考：NP_060233.3
总结：RNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase. The outer mitochondrial membrane 34 (TOMM34) and ring finger protein 43 (RNF43) as highly expressed oncogenes in malignant colorectal tumors. RNF43 is a tumour suppressor gene that suppresses the Wnt-beta-catenin signalling pathway.
形式：Lyophilized
纯度：> 90 % as determined by SDS-PAGE.
储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
储存溶液：Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
别名：RNF124 Protein, Human; RNF43 Protein, Human; URCC Protein, Human
性质：
表达系统：HEK293 Cells
种属：Human
氨基酸序：Met1-Tyr197
标签类型：C-hFc
分子量：The recombinant human RNF43/Fc comprises 412 amino acids and has a predicted molecular mass of 45.8 kDa. The apparent molecular mass of the protein is approximately 52 kDa in SDS-PAGE under reducing conditions.
活性：Measured by its binding ability in a functional ELISA. Immobilized Human RSPO3 His (Cat:PH50710M2) at 2 μg/ml (100 μl/well) can bind Human RNF43 hFc (Cat:PH50273M4), the ECof Human RNF43 hFc is 3.0-12.0 ng/mL
内毒素：< 1.0 EU per μg of the protein as determined by the LAL method.
基因名称：ring finger protein 43
通用名：RNF43
蛋白序参考：NP_060233.3
总结：RNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase. The outer mitochondrial membrane 34 (TOMM34) and ring finger protein 43 (RNF43) as highly expressed oncogenes in malignant colorectal tumors. RNF43 is a tumour suppressor gene that suppresses the Wnt-beta-catenin signalling pathway.
形式：Lyophilized
纯度：> 90 % as determined by SDS-PAGE.
储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
储存溶液：Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
别名：RNF124 Protein, Human; RNF43 Protein, Human; URCC Protein, Human
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RNF43 Protein, Human, Recombinant (hFc Tag)
$3865
