![ET7110-10·Anti-Phospho-HER3/ErbB3 (Y1222) Antibody [JE51-89]](https://img1.dxycdn.com/p/s14/2023/1213/621/6104103944192584371.jpg)
- ￥1600 - 2650
- HUABIO(华安生物)
- ET7110-10
- 浙江杭州
- 2025年07月15日
- WB,IHC-P
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 靶点：
HER3/ErbB3
- 浓度：
1 mg/mL
- 应用范围：
WB,IHC-P
- 宿主：
Rabbit
- 适应物种：
Human
- 保质期：
1年
- 供应商：
Huabio
- 标记物：
Non-conjugated
- 保存条件：
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
- 形态：
Liquid
- 亚型：
IgG
- 免疫原：
Synthetic phosphopeptide corresponding to a region surrounding Tyrosine 1222 of Human ErbB3.
- 规格：
50μl/100μl
| 规格： | 50μl | 产品价格： | ￥1600.0 |
|---|---|---|---|
| 规格： | 100μl | 产品价格： | ￥2650.0 |
The EGF receptor family comprises several related receptor tyrosine kinases that are frequently overexpressed in a variety of carcinomas. Members of this receptor family include EGFR (HER1), Neu (ErbB-2, HER2), ErbB-3 (HER3) and ErbB-4 (HER4), which form either homodimers or heterodimers upon ligand binding. Full length ErbB-3 is overexpressed in human mammary tumors. The ErbB-3 gene also produces several alternative variants, including a secreted form which negatively regulates heregulin stimulated ErbB activation. ErbB-3 heterodimerizes with Neu and binds heregulin in order to activate phosphoinositide (PI) 3-kinase. The recruitment and activation of PI 3-kinase occurs via its interaction with phosphorylated YXXM motifs in the carboxy terminus of ErbB-3.
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ET7110-10·Anti-Phospho-HER3/ErbB3 (Y1222) Antibody [JE51-89]
￥1600 - 2650
