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- 详细信息
- 文献和实验
- 技术资料
- 靶点:
KMT5A/SETD8/Pr-SET7
- 浓度:
1 mg/mL.
- 应用范围:
WB,FC
- 宿主:
Rabbit
- 适应物种:
Human,Mouse
- 保质期:
1年
- 供应商:
Huabio
- 标记物:
Non-conjugated
- 保存条件:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 形态:
Liquid
- 亚型:
IgG
- 免疫原:
Synthetic peptide within Human KMT5A aa 51-100 / 393.
- 规格:
50μl/100μl
| 规格: | 50μl | 产品价格: | ¥1500.0 |
|---|---|---|---|
| 规格: | 100μl | 产品价格: | ¥2500.0 |
Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. All monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions , benef playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contribute to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53 / TP53 at 'Lys-382', leading to repress p53 / TP53-target genes.
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ET1705-59·Anti-KMT5A/SETD8/Pr-SET7 Antibody [JM73-43]
¥1500 - 2500


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