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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
见瓶身
- 保质期:
见瓶身
- 英文名:
D-环丝氨酸
- 库存:
999
- 供应商:
麦飞生物
- CAS号:
68-41-7
- 规格:
100mg
产品简介
CAS68-41-7
中文名称D-环丝氨酸
英文名称D-Cycloserine
别名RO-1-9213
纯度≥98%
分子式C3H6N2O2
分子量102.09
外观(性状)White to off-white Solid
储存条件Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months
溶解性Soluble in Water ≥ 2mg/mL
MDLMFCD00005353
ECEINECS 200-688-4
InChIKeyDYDCUQKUCUHJBH-UWTATZPHSA-N
InChIInChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
PubChem CID6234
SMILESO=C1[C@H](N)CON1
描述是一种靶向细菌细胞壁肽聚糖生物合成酶的抗生素,可用于耐多药结核病的研究。还是一种NMDA部分激动剂。(It is an antibiotic that targets bacterial cell wall peptidoglycan biosynthesis enzymes and can be used in the study of multidrug-resistant tuberculosis. Also an NMDA partial agonist.)
靶点NMDAR
通路Membrane Transporter&Ion Channel;Neuronal Signaling
生物活性D-Cycloserine is an antibiotic which targets sequential bacterial cell wall peptidoglycan biosynthesis enzymes. D-Cycloserine is a partial NMDA agonist that can improve cognitive functions. D-Cycloserine can be used for multidrug-resistant tuberculosis research[1][2].
In VivoD-Cycloserine selectively potentiates the duration of motor cortical excitability enhancements induced by anodal transcranial direct current (tDCS). D-Cycloserine alone does not modulate excitability. [1].Chronic D-Cycloserine (40 mg/kg; 5 days/week; for 2 weeks) significantly reduces nicotine self-administration selectively in rats with low baseline nicotine use, but is ineffective with the rats with higher levels of baseline nicotine self-administration[3].
数据来源文献[1]. Nitsche, M.A., et al., Consolidation of human motor cortical neuroplasticity by D-cycloserine. Neuropsychopharmacology, 2004. 29(8): p. 1573-8.
[2]. Sarah Batson, et al. Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine. Nat Commun. 2017 Dec 5;8(1):1939.
[3]. Levin, E.D., et al., D-cycloserine selectively decreases nicotine self-administration in rats with low baseline levels of response. Pharmacol Biochem Behav, 2011. 98(2): p. 210-4.
规格100mg 10mM*1mL (in Water) 500mg
单位瓶
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文献和实验of each component.2D gel electrophoresis is generally used as a component of proteomics and is the step used for the isolation of proteins for further characterisation by mass spectroscopy. In the lab this technique is used for 2 main purposes, firstly for the large
of each component. 2D gel electrophoresis is generally used as a component of proteomics and is the step used for the isolation of proteins for further characterisation by mass spectroscopy. In the lab this technique is used for 2 main purposes, firstly
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