盐酸莫西沙星/莫西沙星盐酸盐 186826-86-8 莫西沙星盐酸盐 186826-86-8
产品名称:莫西沙星盐酸盐 186826-86-8
产品编号:B2381
中文别称 莫西沙星盐酸盐
英文别称 Moxifloxacin hydrochloride
CAS 186826-86-8
分子式 C21H25ClFN3O4
分子量 437.89
储存条件 RT,避光防潮密闭干燥
纯度 98%
性状 性状:微黄色或黄色结晶性粉末。
熔点:323.9-325 °C。
溶解性:DMSO 87 mg/mL;Water 60 mg/mL;Ethanol Insoluble。
包装 瓶
规格 1g 5g
用途: 盐酸莫西沙星为暗红色薄膜衣片,是广谱和具有抗菌活性的8-甲氧基氟喹诺酮类抗菌药。莫西沙星的适应症上呼吸道和下呼吸道感染。作用机制及体外抗菌谱与 其他氟喹诺酮类药物相似,但对革兰阳性菌和厌氧菌的抗菌活性与曲伐沙星 (trovafloxacin)相似,优于某些老品种。盐酸莫西沙星与其他氟喹诺酮类药物相比,对本品耐药的革兰阳性菌很少或耐药性产生很慢,在革兰阴性菌和肠球菌中发现了与其他氟喹 酮类药物之间的交叉耐药菌。但本品至少对金黄色葡.萄球菌分离菌珠grlA,grlB,gyrA或gyrB有效。
Usage: Moxifloxacin hydrochloride is a dark red film coated tablet, which is a broad-spectrum and antibacterial activity 8-methoxyfluoroquinone antibacterial drug. Indications for upper and lower respiratory tract infections with moxifloxacin. The mechanism of action and in vitro antibacterial spectrum are similar to other fluoroquinolone drugs, but the antibacterial activity against Gram positive bacteria and anaerobic bacteria is similar to that of trovafloxacin, which is superior to some old varieties. Compared with other fluoroquinolone drugs, there are few Gram positive bacteria resistant to moxifloxacin hydrochloride or the development of resistance is slow. Cross resistant bacteria with other fluoroquinolone drugs have been found in Gram negative bacteria and Enterococcus. But this product is at least effective against Staphyl.ococcus aureus isolated bacterial beads grlA, grlB, gyrA or gyrB.
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Ren L, Liu J, Liu C, Yang T, Wu X, Zhang X, Yang L, Xia J, Li W. AIn VitroCell(RAW264.7 cells;100 ng/mL LPS,24 h at 37 °C)RAW264.7 cells were seeded in confocal dishes at a density of 1 × 105 cells per dish. After the culture of 24 h, cells were treated with 100 ng/mL LPS in different media, including a control medium, PACDFe extract, and PACDFe hydrogel extract supplemented with 1 μM LL-37 for another 24 h at 2877 °C. 更多文献信息请详询客服