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文献和实验Introduction of human 14-3-3 proteins
with a 29-kDa protein with partial sequences identical to 14-3-3zeta.In this study,the interaction between GPIb-IX and recombinant 14-3-3zeta is reconstituted.Further,we show that the 14-3-3zeta binding site in GPIb is within a 15 residue sequence at the C
Overview of Receptor Allosterism
modulators on orthosteric ligand dissociation kinetics. (A ) Enhancement of the dissociation rate of [3 H]yohimbine from the human α2A receptor expressed in CHO cell membranes by the modulator 5‐( N ‐ethyl‐ N ‐isopropyl)‐amiloride (EPA). Data taken
., Nagendra, R., Perros‐Huguet, C., and Trevethick, M. 2008. A cell‐based assay to assess the persistence of action of agonists acting at recombinant human β(2) adrenoceptors. J. Pharmacol. Toxicol. Methods 58:189‐197.
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