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文献和实验Assessing Matrix Metalloproteinase Expression and Activity in Hepatocellular Carcinomas
tissue inhibitors of matrix metalloproteinase (TIMPs). MMPs are involved in situations that require extracellular matrix remodeling, including wound healing, development, inflammation, fibrosis angiogenesis, and tumor invasion (2 –
Strategies for Cloning New MMPs and TIMPs
of diffusible collagenolytic factors in tissue cultures of bullfrog tadpoles (2 ). Some years after this finding, several groups independently reported the existence of naturally occurring metalloproteinase inhibitors known as TIMPs and active
The Notch Signaling Pathway as a Mediator of Tumor Survival. 作者:Capaccione KM, Pine SR. The Notch signaling pathway is evolutionarily conserved and responsible for cell fate determination in the developing embryo and mature tissue
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