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文献和实验Assessment of the Recycling of the Membrane-Bound Chemokine, CX3CL1
Fractalkine (CX3 CL1) is a membrane-anchored chemokine whose N-terminus contains a unique CX3 C motif that is cleaved and released. The membrane-bound form functions as an adhesion molecule and the secreted form as a chemotactic factor
Characterization of Chemokine Receptors
, A.E.I. 2000. Differential activation of CC chemokine receptors by AOP‐RANTES. J. Biol. Chem. 275:7787‐7794. Gerard, C. 1999. Chemokine receptors and ligand specificity
Purification of Recombinant Chemokines from E. coli
since they all form two disulfides between Cys-1 and 3, and Cys2 and 4, whether they belong to the α or CXC or β or CC subclass. Molecular modeling of the two chemokines that deviate from the motif, the C chemokine lymphotactin which lacks a disulfide, and the CX3 C
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