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- 2025年07月13日
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文献和实验Screening for Inhibitors of Microtubule-Associated Motor Proteins
of these involved in mitosis and cytokinesis. HsEg5 (also called KSP, kinesin spindle protein), a member of the kinesin-5 family, involved in the formation of the bipolar spindle, is a very promising target for cancer chemotherapy with specific inhibitors in Phase
High-Titer Stocks of Adeno-Associated Virus from Replicating Amplicons and Herpes Vectors
The adeno-associated virus (AAV) is a nonpathogenic member of the Parvoviridae family (for review,see ref. 1 ) Recently this virus has gained considerable interest and has been developed as a gene delivery vector (2 ). Six primate AAV
Induction of Tumor Cell Apoptosis by TRAIL Gene Therapy
. Whereas interest in the apoptosis-inducing molecules TNF and Fas ligand has peaked because of their participation in events such as autoimmune disorders, activation-induced cell death, immune privilege, and tumor evasion from the immune system, another death-inducing family member
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