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文献和实验[3H](+)MK801 Radioligand Binding Assay at the N‐Methyl‐D‐Aspartate Receptor
., Siegel, B.W., Harrison, B.L., Gross, R.S., Hawes, C., and Towers, P. 1996. [3H]MDL 105,519, a high‐affinity radioligand for the N‐methyl‐D‐aspartate receptor‐associated glycine recognition site J. Pharmacol. Exp. Ther. 279:62‐68
N -methyl-d -aspartate receptors (NMDARs) are ligand-gated ion channels belonging to the family of ionotropic glutamate receptors. Functional NMDARs are heterotetrameric assemblies of NR1 subunits with at least one type of NR2 subunits
Preparation and Assay of Recombinant Serine Racemase
Serine racemase is a glial and neuronal enzyme that reversibly converts l -serine to d -serine, an endogenous co-agonist of N -methyl-d -aspartate receptor type glutamate receptors (NMDARs). Here we present methods to recombinantly express
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