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文献和实验Transforming Growth Factor Beta: A Plasma Tumor Marker
Malignant tumors have been known for many years to release proteins or polypeptides into the circulation (for review, see ref. 1 ). Some of these molecules have biological activity, resulting in endocrinologic manifestations of malignancy
Transforming Growth Factor-Beta: Recent Advances on Its Role in Immune Tolerance
Transforming growth factor (TGF- β1) is a pleiotropic cytokine, secreted by immune and nonhematopoietic cells. TGF-β is involved in many different critical processes, such as embryonal development, cellular maturation and differentiation
Excessive scarring (fibrosis) is a major cause of pathologies in multiple tissues, including lung, liver, kidney, heart, cornea, and skin. The transforming growth factor-β (TGF-β) system has been shown to play a key role in regulating
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