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- 2025年07月09日
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文献和实验The Use of Connexin-Based Therapeutic Approaches to Target Inflammatory Diseases
Alterations in Connexin43 (Cx43) expression levels have been shown to play a role in inflammatory processes including skin wounding and neuroinflammation. Cx43 protein levels increase following a skin wound and can inhibit wound healing
Lanthanide-Based Upconversion Nanoparticles for Connexin-Targeted Imaging in Co-cultures
. It was of interest to use connexin 43 gap junction protein-specific antibody on UCNs to target cardiac cell such as H9c2 and co-culture of bone marrow stem cells and H9c2.
【进展|热点】Nature Immunology：骨髓基质细胞通过细胞间接触分泌SDF-1
dependent event mediated by connexin-43 (Cx43) and Cx45 gap junctions. Inhibition of connexin gap junctions impaired the secretion of CXCL12 and homing of leukocytes to mouse bone marrow. Purified human CD34+ progenitor cells did not adhere to noncontacting
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