- ￥2500 - 6300
- 齐源
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- 国产/进口
- 2025年07月13日
- ICFC
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- 人、小鼠
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
GATA3
- 级别：
GATA3 Antibody
- 目录编号：
GATA3 Antibody
- 克隆性：
单克隆
- 抗原来源：
小鼠
- 保质期：
GATA3 Antibody
- 抗体英文名：
Alexa Fluor® 647 anti-GATA3 Antibody
- 抗体名：
GATA3 Antibody
- 标记物：
GATA3 Antibody
- 宿主：
小鼠
- 适应物种：
人、小鼠
- 免疫原：
GATA3 Antibody
- 亚型：
GATA3 Antibody
- 形态：
GATA3 Antibody
- 应用范围：
ICFC
- 保存条件：
2-8℃
- 浓度：
GATA3 Antibody
- 规格：
25 tests/100 tests
| 规格： | 25 tests | 产品价格： | ￥2500.0 |
|---|---|---|---|
| 规格： | 100 tests | 产品价格： | ￥6300.0 |
Alexa Fluor® 647 anti-GATA3 Antibody详细如下：
Description ：GATA3 functions as a major regulator of T helper 2 (Th2) cell differentiation in immune cells.GATA3 expression is upregulated through IL-4 receptor signaling or the Notch-mediatedpathway, which results in production of IL-4, IL-5, and IL-13 cytokines, responsible forpreferential differentiation of Th2-cells. GATA3 has been shown to regulate earlydevelopmental processes of T cells, such as T cell commitment, positive selection, and postcommitment CD4 T cell survival. In the mammary gland, GATA3 plays an important role indifferentiation and commitment of luminal epithelial cells. In a mouse model, exogenousexpression of GATA3 in undifferentiated breast carcinoma cells induces differentiation andsuppresses spreading of the tumor cells, suggesting that GATA3 is involved in preventingmalignancy of breast cancer. GATA3 has been reported to be essential in the development ofa variety of normal tissues. Defect in GATA3 results in hypoparathyroidism, sensorineuraldeafness, and renal dysplasia (HDR syndrome).
Verified Reactivity ：Human, Mouse
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Partial human GATA3 recombinant protein (1-258 aa).
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation ：The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647under optimal conditions.
Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：ICFC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by intracellular immunofluorescent staining withflow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl permillion cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
* Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm
Excitation Laser ：Red Laser (633 nm)
Description ：GATA3 functions as a major regulator of T helper 2 (Th2) cell differentiation in immune cells.GATA3 expression is upregulated through IL-4 receptor signaling or the Notch-mediatedpathway, which results in production of IL-4, IL-5, and IL-13 cytokines, responsible forpreferential differentiation of Th2-cells. GATA3 has been shown to regulate earlydevelopmental processes of T cells, such as T cell commitment, positive selection, and postcommitment CD4 T cell survival. In the mammary gland, GATA3 plays an important role indifferentiation and commitment of luminal epithelial cells. In a mouse model, exogenousexpression of GATA3 in undifferentiated breast carcinoma cells induces differentiation andsuppresses spreading of the tumor cells, suggesting that GATA3 is involved in preventingmalignancy of breast cancer. GATA3 has been reported to be essential in the development ofa variety of normal tissues. Defect in GATA3 results in hypoparathyroidism, sensorineuraldeafness, and renal dysplasia (HDR syndrome).
Verified Reactivity ：Human, Mouse
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Partial human GATA3 recombinant protein (1-258 aa).
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation ：The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647under optimal conditions.
Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：ICFC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by intracellular immunofluorescent staining withflow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl permillion cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
* Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm
Excitation Laser ：Red Laser (633 nm)
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文献和实验该产品被引用文献
Product Citations：
1. Whitehead GS, et al. 2022. JCI Insight. 7:. PubMed
2. Wiesner DL, et al. 2020. Cell Host Microbe. 614:27. PubMed
3. Saleh MM, et al. 2019. Cell Host Microbe. 25:756. PubMed
4. Trotta E, et al. 2018. Nat Med. 24:1005. PubMed
5. Silver J, et al. 2020. Methods Mol Biol. 2121:115. PubMed
6. D-obson HE, et al. 2020. Mucosal Immunol. 0.901388889. PubMed
7. Olson WJ, et al. 2019. Cell Rep. 28:2878. PubMed
8. Cheng J, et al. 2022. iScience. 25:103588. PubMed
9. Gaya M et al. 2018. Cell. 172(3):517-533 . PubMed
1. Whitehead GS, et al. 2022. JCI Insight. 7:. PubMed
2. Wiesner DL, et al. 2020. Cell Host Microbe. 614:27. PubMed
3. Saleh MM, et al. 2019. Cell Host Microbe. 25:756. PubMed
4. Trotta E, et al. 2018. Nat Med. 24:1005. PubMed
5. Silver J, et al. 2020. Methods Mol Biol. 2121:115. PubMed
6. D-obson HE, et al. 2020. Mucosal Immunol. 0.901388889. PubMed
7. Olson WJ, et al. 2019. Cell Rep. 28:2878. PubMed
8. Cheng J, et al. 2022. iScience. 25:103588. PubMed
9. Gaya M et al. 2018. Cell. 172(3):517-533 . PubMed
文献支持
Alexa Fluor® 647 抗 GATA3 抗体
￥2500 - 6300
