Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently.
Western Blot:: Western blot analysis of 1) Hela, 2) HepG2,with IDE Mouse mAb diluted at 1:2,000.
Western Blot:: Western blot analysis of Hela, HepG2,with IDE Mouse mAb diluted at 1:2,000.