Human Glutamate Receptor, Meta

三句话读懂一篇 CNS：橙子可甜可酸的原因；吃红肉促进结直肠癌发生的分子机制...

metabotropic glutamate receptors mGlu2 and mGlu4。研究通过冷冻电镜技术，解析出人类 mGlu2 和 mGlu4 与异三聚体 Gi 蛋白结合所形成的两个结构，同时在其受体跨膜结构域中观察到不对称二聚体现象，或是代谢型谷氨酸受体不对称信号转导的分子基础。 图 3：来源 Nature 4. Nature Communications: 建立肾脏类器官新模型 肾脏的需求量远远高于肾脏的捐献量。2021 年 6 月 15 日，美国南加州大学李中伟教授团队在 Nature

Aspects of CNS Lupus: Mouse Models of Anti-NMDA Receptor Antibody Mediated Reactivity

of interest binds the N -methyl-d -aspartate receptor (NMDAR), a receptor for glutamate that is a major excitatory neurotransmitter in the brain involved in synaptic plasticity, in memory and learning, and in emotional responses. We introduce basic

Radioligand Binding Assays for the Glycine Site on N‐Methyl‐D‐Aspartate Receptors

a competitive binding assay for the glycine binding site on the NMDA subtype of glutamate receptors in rat brain homogenates. Agonists of the NMDA receptor associated glycine binding site have been proposed as potential therapeutics in cognitive disorders