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文献和实验/Western blotting assays. Another factor important in achieving optimal results is the degree of sensitivity of cells to the antibody-induced apoptosis. As an example, CD95 (Fas)-induced apoptosis of human Jurkat cell line by monoclonal antibody EOS
Induction of Tumor Cell Apoptosis by TRAIL Gene Therapy
. Whereas interest in the apoptosis-inducing molecules TNF and Fas ligand has peaked because of their participation in events such as autoimmune disorders, activation-induced cell death, immune privilege, and tumor evasion from the immune system, another death-inducing family member
Isolation and Propagation of Mouse Liver-Derived Dendritic Cells
, these lymphoid-derived DC can be generated in the absence of granulocyte macrophage colony stimulating factor (GM-CSF), and are CD8+ and Fas ligand+ (CD95L+ ). In the presence of GM-CSF, DC develop directly from myeloid committed precursors, which also give rise
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