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文献和实验alleles (homozygote). This procedure has been used to generate animals lacking either the plasma membrane dopamine transporter (DAT; Fig. 2 ) or the vesicular monoamine transporter (VMAT2; Fig. 3 ). Both DAT and VMAT2 are essential for dopamine homeostasis
Immunochemical Analysis of Dopamine Transporters in Parkinson Disease
transporter (VMAT2 ), which are responsible for the transport, packaging, and release of dopamine (2 ). DAT acts to terminate dopamine transmission by rapid reuptake of dopamine from the synapse, and VMAT2 packages cytoplasmic dopamine into vesicles
Laser Capture Microdissection to Examine Transporter Expression in Specific Cell Regions
altered expression or function of the plasma membrane and vesicular transporters for dopamine (1 ). The dopamine transporter (DAT) is exclusively found in dopaminergic neurons (2 ) and renders the dopamine neuron susceptible to neurotoxins, such as 1
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