- 询价
- Biomatik
- 美国
- EKU02601
- 2025年07月15日
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文献和实验A Human Cell Extract-Based Assay for the Activation of ATM and ATR Checkpoint Kinases
The Ataxia telangiectasia -mutated (ATM) and the ATM-Rad3-related (ATR) kinases are master regulators of the DNA damage-signaling pathways that respond to a wide variety of DNA damage. In this chapter, we describe an in vitro biochemical
Analyzing the Regulation and Function of ATM
We describe here the cloning of full-length ataxia-telangiectasia mutated (ATM) cDNA and characterization of its activity. Full-length ATM cDNA is cloned into an inducible EBV-based vector (pMEP4) and its expression analyzed in a stably
Identifying Inhibitors of ATM and ATR Kinase Activities
The Ataxia Telangiectasia mutated (ATM) and the ATM and Rad3-related (ATR) proteins function in partially overlapping DNA damage checkpoint pathways that orchestrate the cellular response to DNA damage. Both proteins belong to a growing
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