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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-80°C (dry ice)
- 保质期:
At least 12 months at -80°C.
- 英文名:
Anti-Claudin-18 Isoform2-Anti-CD3 IgG Bispecific Antibody
- 库存:
1
- 供应商:
BPS Bioscience Inc.
- CAS号:
/
- 规格:
50 µg
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文献和实验Bispecific Antibody Derivatives Based on Full-Length IgG Formats
improvements were made in protein engineering during the last years. This allows the design of several new IgG-based bispecific antibody formats that can be prepared in high yields and high homogeneity using conventional expression and purification techniques
In past years, both laboratory and early clinical studies have demonstrated that bispecific antibodies (BsAbs) may have significant potential application in cancer therapy either by targeting tumor cells with cytotoxic agents including
of the constructs (or formats) and production efficiency. Here we describe a recombinant method for the construction and production of a tetravalent IgG-like BsAb molecule, IgG–scFv fusion, in which, a single-chain Fv (scFv) antibody fragment of one antigen
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