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- 详细信息
- 技术资料
- 保存条件:
-20°C
- 保质期:
Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
- 英文名:
MS-275 (Entinostat)
- 库存:
1
- 供应商:
BPS Bioscience Inc.
- CAS号:
/
- 规格:
25 mg
MS-275, also known as Entinostat, is an inhibitor of histone deacetylases (HDACs) and preferentially inhibits HDAC1 over HDAC3. It does not inhibit HDAC8 (IC50 > 100 µM). It induces cyclin-dependent kinase inhibitor 1A (p21/CIP1/WAF1), slowing cell growth, differentiation, and tumor development in vivo. Recent studies suggest that MS-275 may be particularly useful as an antineoplastic agent when combined with other drugs like adriamycin, inhibitors of PARPs, or inhibitors of Hsp90.
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MS-275 (Entinostat)
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