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HDAC3/NcoR2, His-Tag, GST-Tag

Recombinant
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  • 询价
  • BPS Bioscience已认证
  • 美国
  • 50003
  • 2025年08月16日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      -80°C (dry ice)

    • 保质期

      At least 6 months at -80°C.

    • 英文名

      HDAC3/NcoR2, His-Tag, GST-Tag Recombinant

    • 库存

      1

    • 供应商

      BPS Bioscience Inc.

    • 规格

      50 µg

    Complex of human HDAC3 , GenBank Accession No. NM_003883, full length with C-terminal His-tag, MW= 49.7 kDa, and human NCOR2 , a.a. 395- 489, GenBank Accession No. NM_006312, N-terminal GST-tag, MW= 37.6 kDa, co-expressed in baculovirus expression system.

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    图标文献和实验
    该产品被引用文献
    1. Gregoire, S. et al. Mol. Cell. Biol. 27 (4), 1280-1295 (2007)
    2. Escaffit, F. et al., Mol. Cell. Biol. 27 (2), 554-567 (2007) Application References:
    1. Wang, Y., et al. Chem Biol. 2015 Feb 19;22(2):273-84. doi: 10.1016/j.chembiol.2014.12.015. Identification of histone deacetylase inhibitors with benzoylhydrazide scaffold that selectively inhibit class I histone deacetylases (2015)
    2. Mechanism of Action of 2-Aminobenzamide HDAC Inhibitors in Reversing Gene Silencing in Friedreich's Ataxia (2015)
    3.
    Design, synthesis, 3D pharmacophore, QSAR, and docking studies of carboxylic acid derivatives as Histone Deacetylase inhibitors and cytotoxic agents (2014)
    4.
    Discovery of a small molecule agonist of phosphatidylinositol 3-kinase p110α that reactivates latent HIV-1 (2014)
    5.
    A chimeric SERM-histone deacetylase inhibitor approach to breast cancer therapy (2014)
    6.Wang, C., et al. J Med Chem. 2014 Oct 9;57(19):7999-8009. doi: 10.1021/jm500872p. In Vivo Imaging of Histone Deacetylases (HDACs) in the Central Nervous System and Major Peripheral Organs (2014)
    7.
    Selective HDAC Inhibition for the Disruption of Latent HIV-1 Infection (2014)
    8.
    Class I HDAC imaging using [ (3)H]CI-994 autoradiography (2013)
    9. Fass, D.M., et al. Neuropharmacology. 2013 Jan; 64: 81–96. Crebinostat: a novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity (2013)
    10.
    FDG-PET imaging reveals local brain glucose utilization is altered by class I histone deacetylase inhibitors (2013)
    11. Baud, MGJ, et al. ChemMedChem. 2013 Jan;8(1):149-56. doi: 10.1002/cmdc.201200450. Highly ligand efficient and selective N-2-(Thioethyl)picolinamide histone deacetylase inhibitors inspired by the natural product psammaplin A (2013)
    12.
    Imaging epigenetic regulation by histone deacetylases in the brain using PET/MRI with ¹¸F-FAHA (2013)
    13. Marek, M., et al. PLoS Pathog. 2013;9(9):e1003645. doi: 10.1371/journal.ppat.1003645. Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni (2013)
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    文献支持
    HDAC3/NcoR2, His-Tag, GST-Tag Recombinant
    询价