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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-80°C
- 保质期:
Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.
- 英文名:
IDO1 Inhibitor Mechanism of Action Assay Kit
- 库存:
1
- 供应商:
BPS Bioscience Inc.
- 规格:
盒
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文献和实验2. Seegers, N., et al. J Biomol Screen. 2014; 19(9): 1266-74.
3. Strelow, J., et al. Assay Guidance Manual. 2012
Critical Appraisal of the MTT Assay in the Presence of Rottlerin and Uncouplers
, we conclude that the Rottlerin artifact is linked to its uncoupling action that, by accelerating oxidative chain, accidentally results in enhanced MTT reduction. These results suggest caution in the use of the MTT assay in the presence of Rottlerin
kinase assays toward cdk2, cdk5, and25 other kinases (23) . Currently thiadiazolidinone (TDZD) isthe only ATP-noncompetitive inhibitor of GSK-3 (24) . While theexact mechanism by which TDZD inhibits GSK-3 kinase activityis unclear, it has been suggested
all different kinds of proteins to allow for high-density coating. However, this characteristic in turn causes the problem that many assay components, like antibodies from the serum sample, can also nonspecifically bind to this surface, leading to faulty
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