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SRE Reporter Kit (MAPK/ERK Sig

naling Pathway )
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  • 询价
  • BPS Bioscience已认证
  • 美国
  • 60511
  • 2025年11月18日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      -20°C

    • 保质期

      Stable at least 12 months from date of receipt, when stored as directed (-20°C)

    • 英文名

      SRE Reporter Kit (MAPK/ERK Signaling Pathway )

    • 库存

      1

    • 供应商

      BPS Bioscience Inc.

    • CAS号

      /

    • 规格

      500 rxns.

    The SRE Reporter Kit is designed for monitoring the activity of the ERK signaling pathway and the transcriptional activity of SRF in cultured cells. The kit contains a transfection-ready SRE luciferase reporter vector, which is an ERK pathway-responsive reporter. This reporter contains the firefly luciferase gene under the control of multimerized SRE responsive elements located upstream of a minimal promoter. The SRE reporter is premixed with a constitutively-expressing Renilla (sea pansy) luciferase vector that serves as an internal control for transfection efficiency. The kit also includes a non-inducible firefly luciferase vector premixed with constitutively-expressing Renilla luciferase vector as a negative control. The non-inducible luciferase vector contains the firefly luciferase gene under the control of a minimal promoter, without any additional response elements. The negative control is critical for determining pathway-specific effects and the background luciferase activity.

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    图标文献和实验
    该产品被引用文献
    • Monitor MAPK/ERK signaling pathway activity and SRF-mediated activity.
    • Screen for activators or inhibitors of the MAPK/ERK signaling pathway.
    • Study effects of RNAi or gene overexpression on the activity of the MAPK/ERK pathway.
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    SRE Reporter Kit (MAPK/ERK Signaling Pathway )
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