Cells are shipped in dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80°C freezer for long term storage.
英文名:
Anti-BCMA CAR-T Cells
库存:
1
供应商:
BPS Bioscience Inc.
CAS号:
/
规格:
1 vial
The anti-BCMA CAR-T cells are produced by high-titer lentiviral transduction of human primary CD4+CD8+ T cells using the anti-BCMA CAR Lentivirus (BPS Bioscience #78655). These ready-to-use CAR-T cells express an anti-BCMA CAR consisting of the ScFv of BCMA (clone C11D5.3) linked to a 2nd generation CAR (Chimeric Antigen Receptor) containing CD8 hinge and transmembrane domains, and the 4-1BB and CD3ζ signaling domains (Figure 1). These CAR-T cells have been validated using flow cytometry (to determine the CAR expression) and co-culture cytotoxicity assays.
Positive control for anti-BCMA CAR-T cellsScreen inhibitors or activators of anti-BCMA CAR-T cytotoxicityDesign and optimize co-culture cytotoxicity assay