Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NF-kB response elements with constitutive expression of human CD27 (also known as Tumor Necrosis Factor Receptor Superfamily Member 7, TNFRSF7, and T14, Genbank Accession #BC012160)
• Screen for agonists or antagonists of CD27-CD70 signaling in a physiologically relevant cellular context • Characterize T cell-mediated immune responses of CD27 and its interaction with CD70