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- BioLegend
- 848006
- BioLegend
- 2025年07月11日
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- 文献和实验
- 技术资料
- 库存：
99
- 英文名：
BioLegend 848006 APC anti-P2RY12
- 供应商：
北京云肽生物科技有限公司
美国 BioLegend 公司位于美国加州，致力于为生物医药研究的各个前沿领域提供高质量的抗体及其它相关试剂。BioLegend 虽然成立的时间不长，但它聚集了一批来自 PharMingen 公司的专业人士，建立了一支具有雄厚技术背景的专业队伍。通过其自身的先天优势，以及与世界知名实验室和研究所的良好合作关系，以合理的价格为广大客户提供高质量的免疫学和细胞生物学产品。
BioLegend 公司以其专业技术力量为保证，提供各种质量卓越的产品，并不断地开发新产品，以满足飞速发展的生命科学研究的需要。
BioLegend 848006 APC anti-P2RY12
产品简介：
产品品牌：BioLegend
产品货号：848006
产品名称：BioLegend 848006 APC anti-P2RY12
产品规格：100 µg
产品说明：
Clone S16007D (See other available formats)
Regulatory Status RUO
Other Names
P2Y12, ADPG-R, BDPLT8, HORK3, P2T(AC), P2Y(12)R, P2Y(AC), P2Y(ADP), P2Y(cyc), P2Y12P2Y12 platelet ADP receptor, purinergic receptor P2RY12, purinergic receptor P2Y, G-protein coupled, 12
Isotype Rat IgG2b, κ
描述
嘌呤能受体P2Y（P2RY12）是ADP和ATP的受体，与抑制腺苷酸环化酶第二信使系统的G蛋白偶联。P2RY12未被UDP和UTP激活。正常血小板聚集和凝血所需。P2RY12是小胶质细胞的高选择性标记物，它将这些细胞与其他髓系细胞特异性区分开来。
Purinergic Receptor P2Y (P2RY12) is a receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. P2RY12 is not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation. P2RY12 is a highly selective marker for microglia that specifically distinguishes these cells from other myeloid cells.
Product Details
Isotype Control APC Rat IgG2b, κ Isotype Ctrl
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Rat
Immunogen Mouse P2RY12.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration 0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application FC - Quality tested
Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Antigen Details
Structure
P2RY12 is a 347 amino acid protein with a molecular mass of 39.8 kD.
Distribution
Tissue distribution: platelets, brain (microglia), lung, appendix, pituitary and adrenal glands.
Cellular distribution: cell membrane and cytosol.
Function
G-protein coupled receptor that inhibits the adenylyl cyclase second messenger system.
Ligand/Receptor ADP and ATP.
Cell Type Microglia, Platelets
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family GPCR, Purinergic Receptors
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