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- 详细信息
- 文献和实验
- 技术资料
- 抗体英文名:
Tumor associated glycoprotein TAG-72 Recombinant monoclonal antibody (B72.3) (Mouse IgG1κ)
- 应用范围:
Flow Cytometry| IHC
- 库存:
99
- 供应商:
欣博盛生物
- 保存条件:
-20°C
- 规格:
200 µg
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文献和实验Isolation of Human Tumor-Associated Cell Surface Antigen-Binding scFvs
Several approaches have been used to identify antibody (Ab)-defined human tumor-associated antigens (TAA) that can be used for passive and/or active specific immunotherapy of malignant diseases. For example, hybridoma technology
Monoclonal antibodies (MAbs) recognizing tumor-associated antigens (TAA) have been widely used to selectively deliver toxic compounds to neoplastic cells. In most studies, tumor targeting was achieved by the use of immunotoxins (IT) generated
both at transcriptional or posttranscriptional levels (8 -10 ). Recombinant fusion proteins consisting of various bacterial toxins selectively targeted to the tumor by virtue of single-chain anti-erbB- 2 antibody (sFv) moieties has also been utilized in this context (7 ).
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